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A Model-Based Methodology for Spray-Drying Process Development

Solid amorphous dispersions are frequently used to improve the solubility and, thus, the bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Spray-drying, a well-characterized pharmaceutical unit operation is ideally suited to producing solid amorphous dispersions due to its rapid drying kinetics. This paper describes a novel flowchart methodology based on fundamental engineering models and state-of-the-art …

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Guide to Understanding the Baghouse Filter Bags

Since the Clean Air Act in the 1970s, the utilization of fabric filter baghouses for both process and nuisance dust collection has experienced a 16% compound growth rate worldwide. Growth rates have leveled in the U.S., but maintained themselves in emerging countries. Government and social mandates have brought requirements for larger and more sophisticated baghouse …

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Manufacturing Methods for Production of Pharmaceutical Tablet

A tablet is a pharmaceutical dosage form. It contains of a combination of active substances and excipients, generally in powder form, passed are compacted into a solid dose. Excipients: Diluents, binders or granulating agents, glidents and lubricants to ensure efficient tableting; Disintegrates: to promote tablet break up in the digestive tract; Sweeteners or flavours: to …

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Different Methods of Grain Drying

Grain drying is method of drying grain to stop spoilage throughout storage. The grain drying represented during this article is that which uses fuel- or electric-powered processes supplementary to natural ones, as well as swathing/windrowing for drying by close air and sunshine. Hundreds of millions of tonnes of wheat, corn, soybean, rice and different grains …

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Drying Methods for Improving the Quality of Dried Herbs

Herbs are “any plant with leaves, seeds, or flowers used for seasoning, food, medicine, or perfume”. Herbs are considered to be extremely perishable foods thanks to their high moisture content and most herbs are chill-sensitive. They’re thus processed by drying to make shelf-stable product. Drying preserves the standard of herbs by reducing the moisture content …

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Importance of Granulation Techniques and Technologies

Granulation, the method of particle enlargement by agglomeration technique, is one among the most vital unit operations in the production of pharmaceutical dosage forms, largely tablets and capsules. Granulation method transforms fine powders into free-flowing, dust-free granules that are simple to compress. Nonetheless, granulation poses various challenges because of top quality demand of the formed …

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